PLGA Nanoparticles, Streptavidin Coated

Description
Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Streptavidin protein is covalently conjugated to the surface of the PLGA nanoparticles. Dye molecules and magnetic nanoparticles can be encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry).
 
Features
Made with FDA approved biocompatible and biodegradable PLGA polymer.
Easy loading of antibodies, proteins, and small molecules through Streptavidin – Biotin interaction.
High degree of monodispersity.
(Optional) Can be pulled down by application of magnetic force.
(Optional) Labeled with a fluorescent dye.
 
Applications
Dual labeled fluorescence and magnetic nanoparticles for in-vivo targeting.
Dual fluorescence and MRI imaging for in vitro and in vivo applications.
Dual labeled fluorescence and magnetic probes for magnetic cell pulldown and flowcytometry analysis.
In vitro and in vivo delivery of proteins and small molecules.
 
Product is supplied as suspensino in 1X PBS, pH 7